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Silica based SPE

Compared with low-purity irregular silica, SelectCore silica based SPE cartridges utilize high-purity spherical silica particles as the matrix, and exhibit reproducible recoveries for quick and effective extraction, isolation and concentration of pharmaceuticals from biological fluids and other aqueous sample matrices.
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Compared with low-purity irregular silica, SelectCore silica based SPE cartridges utilize high-purity spherical silica particles as the matrix, and exhibit reproducible recoveries for quick and effective extraction, isolation and concentration of pharmaceuticals from biological fluids and other aqueous sample matrices.


Product

Particle size

Description

SelectCore Silica

50 μm

Polar sorbent, used primarily to adsorb analytes from non-polar solvents like hydrocarbons, chloro- or fluoro-subsitituted hydrocarbons or less polar esters and ethers; elution with more polar solvents like polar esters, ethers, alcohols, acetonitrile or water; the binding mechanism can be hydrogen bonding or dipole-dipole interaction.

SelectCore C18

50 μm

Silica based bonded phase, used to adsorb analytes of even weak hydrophobicity from aqueous solutions; typical applications include drugs and their metabolites in serum, plasma or urine, desalting of peptides, trace organics in environmental water samples, organic acids in beverages.

SelectCore NH2

50 μm

Silica based bonded phase with weakly basic surface; can be used as a polar sorbent, like silica, with different selectivity for acidic/basic analytes or as weak anion exchanger in aqueous medium below pH8; applications include phenols and phenolic pigments, petroleum fractionation, saccharides, drugs and drug metabolites.

SelectCore PSA

50 μm

Silica based phase with ethylenediamine-N-propyl that contains both primary and secondary amines; A weak anion exchanger with a pKa of 10.1 and 10.9; Similar to aminopropyl SPE phases (NH2) in terms of selectivity, but has a much higher capacity due to presence of secondary amine; Strong affinity and high capacity for removing fatty acids, organic acids, and some polar pigments and sugars when conducting multi-residue pesticide analysis in foods.


PackageSilicaC18NH2PSA
100mg/1mL; 100/pkgSI050-010100-1C18050-010100-1NH050-010100-1PSA050-010100-1
200mg/3mL; 50/pkgSI050-030200-1C18050-030200-1NH050-030200-1PSA050-030200-1
500mg/3mL; 50/pkgSI050-030500-1C18050-030500-1NH050-030500-1PSA050-030500-1
500mg/6mL; 30/pkgSI050-060500-1C18050-060500-1NH050-060500-1PSA050-060500-1
1000mg/6mL; 30/pkgSI050-061000-1C18050-061000-1NH050-061000-1PSA050-061000-1