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BioCore SCX is a family of high-performance, strong cation-exchange columns designed for separating charged variants in proteins, including monoclonal antibodies (mAbs) and related biomolecules. Its column technology involves the creation of a hydrophilic sulfonic functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.
Optimal selectivity for separating charged variants in proteins/antibodies
Good peak shape and low carryover
High column efficiency and mechanical strength
Excellent tolerance to acids, bases and organic solvents
Good column-to-column consistency
Product Name | BioCore SCX |
Functional Group | Sulfonic Acid |
Substrate | Monodispersed, spherical, nonporous PS/DVB particles |
Particle Size | 5 & 10 μm |
Pore Size | Nonporous |
Pressure Limit | 5000 psi for 5 μm 4000 psi for 10 μm |
Temperature Limit | 60 ℃ |
pH Range | 2-12 |
Application | Charged variants in antibodies and proteins |
Product Name | Particle Size (µm) | Length (mm) | ID (mm) |
4.6 | |||
BioCore SCX | 10 | 250 | B411-100000-04625P |
150 | B411-100000-04615P | ||
100 | B411-100000-04610P | ||
50 | B411-100000-04605P | ||
5 | 250 | B411-050000-04625P | |
150 | B411-050000-04615P | ||
100 | B411-050000-04610P | ||
50 | B411-050000-04605P |