BioCore SCX is a family of high-performance, strong cation-exchange columns designed for separating charged variants in proteins, including monoclonal antibodies (mAbs) and related biomolecules. Its column technology involves the creation of a hydrophilic sulfonic functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.

Main Features

• Optimal selectivity for separating antibody charged variants

• Good peak shape and low carryover

• High column efficiency and mechanical strength

• Excellent tolerance to acids, bases and organic solvents

• Good column-to-column consistency

Specifications

Applications