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BioCore HPLC columns are based on the most advanced column technology and designed for characterization of proteins by liquid chromatography, including fast titer analysis of monoclonal antibodies (mAb) and Fc fusion proteins, monomer and dimers of mAbs, charged variant and oxidation variant analysis, antibody drug conjugate analysis, intact mAb and mAb fragments analysis, peptide mapping and glycan analysis.
BioCore SEC is a family of high performance, size exclusion chromatography columns designed for separating a broad range of biomolecules based on size.
BioCore WCX is a family of high-performance, weak cation-exchange columns designed for separating charged variants in proteins,including monoclonal antibodies (mAbs) and related substances. Its column technology involves the creation of a hydrophilic carboxylic functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.
BioCore SCX is a family of high-performance, strong cation-exchange columns designed for separating charged variants in proteins, including monoclonal antibodies (mAbs) and related biomolecules. Its column technology involves the creation of a hydrophilic sulfonic functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.
BioCore SAX is a family of high-performance, strong anion-exchange columns designed for separating charged variants in proteins with an isoelectric point below 10. Its column technology involves the creation of a hydrophilic quaternary amino functional layer on the surface of monodispersed, nonporous, spherical PS/DVB particles, in combination with a well-established column packing process.
BioCore HIC-Butyl is a family of high-performance, hydrophobic interaction chromatography columns that separate monoclonal antibodies (mAbs) and Antibody-Drug Conjugates (ADCs) based on their differences in surface hydrophobicity. This column technology involves the creation of a hydrophilic layer decorated with selective hydrophobic functionality, on the surface of monodispersed, wide-pore, spherical, silica particles, in combination with well-established column packing processes.
BioCore RP-Butyl is a family of high-performance, reversed-phase columns that separate intact proteins and protein fragments,including monoclonal antibodies (mAbs) and related substances. This column technology involves attaching butyl functionality onto the surface of monodispersed, nonporous, spherical, PS/DVB particles, in combination with well-established column packing processes.
BioCore Glycan is a family of high-performance HILIC columns designed for profiling N-glycans present in proteins and related substances. This column technology involves the creation of a proprietary hydrophilic layer on the surface of monodispersed,spherical, porous silica particles, in combination with well-established column packing processes.
BioCore Protein A is a family of high-performance-affinity chromatography columns, designed for fast titer analysis of monoclonal antibodies (mAb) and Fc fusion proteins. BioCore Protein A is based on monodispersed, wide-pore, spherical PS/DVB particles, on which alkaline-resistant recombinant protein A ligands are bonded, in combination with well-established column packing processes.
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